Journal Club: Models in Immunology

http://mbi.osu.edu/seminars/mijournal.html#das

Journal Club: Models in Immunology

Organizers: Baltazar Aguda, Jayajit Das, and Avner Friedman

February 23, 2009; 3:00-4:00pm; MBI Auditorium (Room 355, Jennings Hall)

March 23, 2009; 3:00-4:00pm; MBI Auditorium (Room 355, Jennings Hall)

Dr. Jayajit Das, Nationwide Children's Hospital, Batelle Center for Mathematical Medicine

A basic introduction to signaling in our immune system

According to Dr Das: "I will keep the level of the talk at an introductory level where I will introduce the key players of our immune system and describe how they communicate and work together, ending with the key questions that remain to be understood. In the second talk I will be more specific show how mathematical modeling can help in understanding those questions in the context of T cell and NK cell signaling."

The tentative schedule of the succeeding talks is given below:

March 30, 2009; 3:00-4:00pm; MBI Auditorium (Room 355, Jennings Hall)

April 6, 2009; 3:00-4:00pm; MBI Auditorium (Room 355, Jennings Hall)

Baltazar Aguda, MBI

Cancer Immunoediting

April 13, 2009; 3:00-4:00pm; MBI Auditorium (Room 355, Jennings Hall)

April 20, 2009; 3:00-4:00pm; MBI Auditorium (Room 355, Jennings Hall)

Judy Day, MBI

May 4, 2009; 3:00-4:00pm; MBI Auditorium (Room 355, Jennings Hall)

May 11, 2009; 3:00-4:00pm; MBI Auditorium (Room 355, Jennings Hall)

C. Jayaprakash

Imaging in Systems Biology

Sean G. Megason^{1, ,} and Scott E. Fraser^{1, ,}

¹Beckman Institute and Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA

Available online 6 September 2007.

Most systems biology approaches involve determining the structure of biological circuits using genomewide “-omic” analyses. Yet imaging offers the unique advantage of watching biological circuits function over time at single-cell resolution in the intact animal. Here, we discuss the power of integrating imaging tools with more conventional -omic approaches to analyze the biological circuits of microorganisms, plants, and animals.

(link)